In order to get started with podcasting and streaming, you are going to need a decent microphone. For more complex setups, investing in an audio interface makes sense. The UA Volt 176 USB Audio Interface can help. It lets you create podcasts on your Mac, PC, iPad, and iPhone. It has a studio quality headphone amp and 48v phantom power.
This audio interface can be used with Ableton, Melodyne, UJAM’s Virtual Drummer, Marshall, Ampeg, and other top software. The device is USB powered, so you won’t have to deal with too much clutter. More information is available here.